What is the Paleo diet, really – and should I try it?

By now, most people have heard of “the Paleo Diet”: it’s been a widely talked-about and researched dietary approach for some time. The concept of Paleo eating entered the nutrition conversation in the 1970s, but didn’t gain momentum until 2002 with the publication of Loren Cordain’s book, The Paleo Diet: Lose Weight and Get Healthy by Eating the Foods You Were Designed to Eat. [1] In the years since, Paleo-style diets have been the focus of hundreds of books, scientific papers, and professional lectures, with an estimated 3 million people in the US alone adhering to its principles. [2]

bowl of chili and kale salad

Still, it’s understandable if you’re not completely clear on what the Paleo diet entails, and you might be wondering if there’s something truly useful and practical behind what some consider yet another fad diet. We’ll cut through the confusion, break down what the Paleo diet is all about, and look objectively at its effects on human health.

Why “Paleo”?

The Paleo diet draws inspiration from the dietary and environmental influences of the Paleolithic period—an era spanning from 2.5 million years ago to about 10,000 B.C.E., ending with the dawn of agriculture. It was during this time that our early ancestors became anatomically human, undergoing physiological changes as we adapted to different climates, began using stone tools, learned to control fire, and expanded our diet to include more diverse foods. [3] Historical analyses show that the diseases most common today—including heart disease—were extremely rare during this era. [4]

Throughout this period, early humans were mostly nomadic hunter-gatherers who subsisted on a variety of unprocessed foods that they were able to catch or forage. They ate a nutrient-dense array of plants and animals including ruminant meat, small mammals, birds, fish, shellfish, reptiles, vegetables, fruits, berries, tubers, roots, nuts, honey, insects, and whatever else the local environment provided.

Importantly, there was a complete absence of many of the foods and ingredients that dominate store shelves today—including grains, refined sugar, vegetable oils, processed dairy, chemical additives, artificial sweeteners, and preservatives.

As a result, the Paleo diet is a basic framework encompassing nutrient density, dietary diversity, whole-foods eating, and the avoidance of harmful modern allergens and food-like products.

Inspiration vs. reenactment

One of the common misconceptions about Paleo-style eating is that it’s based on historical reenactment—that is, trying to re-create the exact diet and lifestyle of Paleolithic humans. This is far from the case! Rather, the Paleo diet takes a big-picture approach to human nutritional needs, helping identify the features of the modern diet and lifestyle that are out of alignment with the human body’s design.

Ultimately, it’s impossible to eat the exact same vegetables, fruits, and animal species that our early ancestors did. Many Paleolithic era staples (such as megafauna like mammoths and mastodons) are now extinct, and thousands of years of evolution and cultivation have rendered today’s plant foods unrecognizable from what they were historically. And so, rather than implying we try to literally eat like cavemen, the Paleo diet suggests we look at the overarching dietary patterns our bodies spent millennia adapting to. In doing so, we find clues for what’s best for us today.

These broad dietary patterns include:

Importantly, these Paleo-inspired nutritional tenets are backed by modern science, with studies showing they individually and collectively protect against chronic diseases. These include:

To help avoid fixating on a specific era in history, or incorrectly conjuring images of caveman reenactment, terms like “ancestral eating” or “primal” are sometimes used to describe this way of eating. Likewise, some eating plans use ancestrally aligned principles without specifically calling themselves Paleo, such as the Whole30 Program.

So, what exactly does Paleo eating look like?

Although the Paleo diet is rooted in some core principles, in practice, it offers abundant flexibility and room for individual tailoring. As a starting place, it includes whole or minimally processed foods from the following categories:

cooked shrimps in stainless steel sauce pan

In addition, some people choose to include “gray zone” foods that vary in their individual tolerance. These include:

By contrast, a Paleo diet excludes:

How much you eat of each Paleo-friendly food is up to you, but in general, striving for diversity of both plant and animal foods helps ensure a wide intake of different vitamins, minerals, and phytochemicals. An example of a Paleo plate would be some form of protein (eggs, fish, poultry, pork, or beef), a non-starchy green vegetable (such as leafy greens or broccoli), a healthy fat source (like an avocado, nuts, or olive oil), and a nutrient-dense carbohydrate food (like a sweet potato or fruit).

Individual tailoring

Some people further tailor their Paleo diet to fit additional nutritional needs—such as avoiding foods that trigger autoimmune reactions (per the Autoimmune Protocol), limiting high-FODMAP foods to help manage IBS, avoiding nuts or seafood due to allergies, eating within ketogenic ratios, and other modifications.

Likewise, some people strive to optimize food quality and sustainability by eating locally and seasonally, choosing organic or pesticide-free produce, and seeking out grass-fed or free-range animal products. While these are excellent goals with many benefits for both human health and the planet, they’re not mandatory for following a Paleo diet—especially if doing so makes eating Paleo impractical or financially untenable for your current situation.

In short, Paleo eating will look different for different people, as we all have our preferences, goals, and intolerances. Some of us will enjoy more carbs from fruits and roots, some of us will eat more or less red meat, and some of us might make Paleo pancakes on the weekends: these are all versions of Paleo eating!

Is the Paleo diet low carb?

The Paleo diet sometimes gets portrayed as a meat-heavy, low-carbohydrate diet, but in practice, this way of eating is “macronutrient agnostic”—meaning it can encompass a wide range of fat, carbohydrate, and protein intakes, as long as the foods being consumed fit into the general Paleo framework.

Part of the confusion comes from difficulty in assessing the plant food intake of early humans. Unlike the bones, shells, and other physical remains left after butchering animals, evidence of plant food consumption disintegrates quickly and leaves fewer traces. As a result, animal foods may be over-represented at archeological sites where Paleolithic humans lived, giving a false impression that ancestral eating should be meat-dominant and low-carb.

However, other forms of evidence (including human anatomical changes, dentition, and carbon isotope analyses) show that early humans were eating higher-carbohydrate foods like roots and tubers for hundreds of thousands of years, if not longer. [14] [15] Paleo diet reconstructions, based on food availability in East Africa, estimate that Paleolithic humans were getting about 40% of their energy from carbohydrates. [16] Likewise, modern hunter-gatherer populations—which scientists sometimes study for clues about pre-modernized diets—have a wide range of carbohydrate intakes, spanning from 3% to 50% of total energy. [17]

There’s also genetic evidence for humans adapting to starch consumption, through selective increases in the number of carbohydrate-degrading salivary amylase gene copies (AMY1) we carry relative to other primates. [18]

In short, there’s no explicit rule to keep carbohydrate levels in a certain range while following a Paleo diet; doing so is a matter of personal choice. The heart of Paleo is eating ancestrally aligned foods rather than tracking numbers!

Didn’t cavemen live short lives?

A common criticism of the Paleo diet is that compared to modern humans, our Paleolithic ancestors had much shorter life expectancies—by some estimates, living only 33 years on average, with a mere 60% chance of even reaching age 15. [19] On the surface, this seems to challenge the logic of eating Paleo: why follow a diet that didn’t promote longevity?

While these numbers are technically true, they’re only a small piece of the puzzle. Unlike the chronic diet and lifestyle-related illnesses that plague humans today, mortality during the Paleolithic period was dominated by injury, infectious disease, high infant mortality, maternal death, and other threats unrelated to diet.

More specifically, about 75% of Paleolithic deaths were caused by infection (including diarrheal diseases that led to dehydration and starvation), an additional 15% of deaths were from violent injury, and about 1 out of every 100 mothers died in labor. [20] Average life expectancy was skewed significantly downwards as a result of these factors.

Thanks to modern medicine, sanitation, and other life-saving advancements, most of these environmental threats have been greatly reduced or eliminated as causes of death. Our greatest killers are now chronic in nature—diet and lifestyle-driven diseases such as cancer, heart disease, and diabetes. It’s in protecting against these diseases that the Paleo diet really shines.

What does the research say?

To date, hundreds of studies have been published on Paleo-style diets—including intervention trials, observational studies, and comparisons with other popular eating plans. The results of these studies show that Paleo eating:

Importantly, research shows that perfect adherence isn’t necessary to obtain the benefits of this eating style; the closer you can eat to Paleo, the better! Studies using dietary adherence scores—in which people’s diets are assessed based on how closely they follow specific eating protocols—find that the more people’s diets resemble Paleo eating, the more their risk of cardiovascular disease, cancer death, and all-cause mortality drops. [45] [46] [47]

In other words, every step you take towards a Paleo-style diet should reap substantial benefits. If strict adherence seems too daunting, making whatever changes you can towards anti-inflammatory, nutrient-dense foods will pay off.

Is there more to Paleo than just food?

Although it’s typically referred to as a diet, the Paleo framework is ultimately about more than just food. It’s an overall approach to living in alignment with how our bodies are evolved to thrive, even within the context of our modern-day challenges and lifestyles.

Drawing lessons from the resilience of our ancestors, Paleo advocates also encourage lots of easy, low-level movement, functional strength training, time outdoors in the sunshine, an active approach to optimal sleep in line with our circadian rhythms, fostering good relationships, and stress management. Not only are these key features of ancestral living (most of which have only been lost relatively recently in human history); science confirms that these lifestyle elements, too, are strongly protective against chronic disease. [48] [49] [50] [51] [52]

At first, the Paleo diet might seem like a sharp pivot from the ways of eating and living that most of us are used to. But in essence, it’s a return to our roots. No matter where you’re starting from or how strictly you choose to follow Paleo-style principles, any movement closer to ancestral alignment is likely to positively impact your health and quality of life. You deserve to feel great!


References

  1. Challa HJ, Bandlamudi M, Uppaluri KR. Paleolithic Diet. [Updated 2022 Jul 4]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Jan-. Available from: https://www.ncbi.nlm.nih.gov/books/NBK482457/
  2. Schmidt M. The Paleo Diet: Should Modern Humans Eat the Way Our Ancestors Did? 2020 Aug 18.
  3. Holt BM, Formicola V. Hunters of the Ice Age: The biology of Upper Paleolithic people. Am J Phys Anthropol. 2008;Suppl 47:70-99. doi: 10.1002/ajpa.20950.
  4. O'Keefe JH Jr, Cordain L. Cardiovascular disease resulting from a diet and lifestyle at odds with our Paleolithic genome: how to become a 21st-century hunter-gatherer. Mayo Clin Proc. 2004 Jan;79(1):101-8. doi: 10.4065/79.1.101.
  5. Xu X, Zhang J, Zhang Y, Qi H, Wang P. Associations between dietary fiber intake and mortality from all causes, cardiovascular disease and cancer: a prospective study. J Transl Med. 2022 Aug 2;20(1):344. doi: 10.1186/s12967-022-03558-6.
  6. da Silva A, Felício MB, Caldas APS, Miranda Hermsdorff HH, Bersch-Ferreira ÂC, Torreglosa CR, Shivappa N, Hébert JR, Weber B, Bressan J. Pro-inflammatory diet is associated with a high number of cardiovascular events and ultra-processed foods consumption in patients in secondary care. Public Health Nutr. 2021 Aug;24(11):3331-3340. doi: 10.1017/S136898002000378X.
  7. Pagliai G, Dinu M, Madarena MP, Bonaccio M, Iacoviello L, Sofi F. Consumption of ultra-processed foods and health status: a systematic review and meta-analysis. Br J Nutr. 2021 Feb 14;125(3):308-318. doi: 10.1017/S0007114520002688.
  8. Troesch B, Biesalski HK, Bos R, Buskens E, Calder PC, Saris WH, Spieldenner J, Verkade HJ, Weber P, Eggersdorfer M. Increased Intake of Foods with High Nutrient Density Can Help to Break the Intergenerational Cycle of Malnutrition and Obesity. Nutrients. 2015 Jul 21;7(7):6016-37. doi: 10.3390/nu7075266.
  9. Simopoulos AP. An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity. Nutrients. 2016 Mar 2;8(3):128. doi: 10.3390/nu8030128.
  10. Berer K, Martínez I, Walker A, Kunkel B, Schmitt-Kopplin P, Walter J, Krishnamoorthy G. Dietary non-fermentable fiber prevents autoimmune neurological disease by changing gut metabolic and immune status. Sci Rep. 2018 Jul 11;8(1):10431. doi: 10.1038/s41598-018-28839-3.
  11. Swann OG, Kilpatrick M, Breslin M, Oddy WH. Dietary fiber and its associations with depression and inflammation. Nutr Rev. 2020 May 1;78(5):394-411. doi: 10.1093/nutrit/nuz072.
  12. DiNicolantonio JJ, O'Keefe J. The Importance of Maintaining a Low Omega-6/Omega-3 Ratio for Reducing the Risk of Autoimmune Diseases, Asthma, and Allergies. Mo Med. 2021 Sep-Oct;118(5):453-459.
  13. Simopoulos AP. Evolutionary aspects of diet, the omega-6/omega-3 ratio and genetic variation: nutritional implications for chronic diseases. Biomed Pharmacother. 2006 Nov;60(9):502-7. doi: 10.1016/j.biopha.2006.07.080.
  14. Laden G, Wrangham R. The rise of the hominids as an adaptive shift in fallback foods: plant underground storage organs (USOs) and australopith origins. J Hum Evol. 2005 Oct;49(4):482-98. doi: 10.1016/j.jhevol.2005.05.007.
  15. Sponheimer M, Alemseged Z, Cerling TE, Grine FE, Kimbel WH, Leakey MG, Lee-Thorp JA, Manthi FK, Reed KE, Wood BA, Wynn JG. Isotopic evidence of early hominin diets. Proc Natl Acad Sci U S A. 2013 Jun 25;110(26):10513–8. doi: 10.1073/pnas.1222579110.
  16. Kuipers RS, Luxwolda MF, Dijck-Brouwer DA, Eaton SB, Crawford MA, Cordain L, Muskiet FA. Estimated macronutrient and fatty acid intakes from an East African Paleolithic diet. Br J Nutr. 2010 Dec;104(11):1666-87. doi: 10.1017/S0007114510002679.
  17. Ströhle A, Hahn A. Diets of modern hunter-gatherers vary substantially in their carbohydrate content depending on ecoenvironments: results from an ethnographic analysis. Nutr Res. 2011 Jun;31(6):429-35. doi: 10.1016/j.nutres.2011.05.003.
  18. Perry GH, Dominy NJ, Claw KG, Lee AS, Fiegler H, Redon R, Werner J, Villanea FA, Mountain JL, Misra R, Carter NP, Lee C, Stone AC. Diet and the evolution of human amylase gene copy number variation. Nat Genet. 2007 Oct;39(10):1256-60. doi: 10.1038/ng2123.
  19. Kaplan H, Hill K, Lancaster J, Hurtado AM. A Theory of Human Life History Evolution: Diet, Intelligence and Longevity (PDF). Evolutionary Anthropology. 2000 Jan;9(4):156-185. doi: 10.1002/1520-6505(2000)9:4<156::AID-EVAN5>3.0.CO;2-7.
  20. Goldman L. Three Stages of Health Encounters Over 8000 Human Generations and How They Inform Future Public Health. Am J Public Health. 2018 Jan;108(1):60-62. doi: 10.2105/AJPH.2017.304164.
  21. Boers I, Muskiet FA, Berkelaar E, Schut E, Penders R, Hoenderdos K, Wichers HJ, Jong MC. Favourable effects of consuming a Palaeolithic-type diet on characteristics of the metabolic syndrome: a randomized controlled pilot-study. Lipids Health Dis. 2014 Oct 11;13:160. doi: 10.1186/1476-511X-13-160.
  22. Pastore RL, Brooks JT, Carbone JW. Paleolithic nutrition improves plasma lipid concentrations of hypercholesterolemic adults to a greater extent than traditional heart-healthy dietary recommendations. Nutr Res. 2015 Jun;35(6):474-9. doi: 10.1016/j.nutres.2015.05.002.
  23. de Menezes EVA, Sampaio HAC, Carioca AAF, Parente NA, Brito FO, Moreira TMM, de Souza ACC, Arruda SPM. Influence of Paleolithic diet on anthropometric markers in chronic diseases: systematic review and meta-analysis. Nutr J. 2019 Jul 23;18(1):41. doi: 10.1186/s12937-019-0457-z.
  24. Ghaedi E, Mohammadi M, Mohammadi H, Ramezani-Jolfaie N, Malekzadeh J, Hosseinzadeh M, Salehi-Abargouei A. Effects of a Paleolithic Diet on Cardiovascular Disease Risk Factors: A Systematic Review and Meta-Analysis of Randomized Controlled Trials. Adv Nutr. 2019 Jul 1;10(4):634-646. doi: 10.1093/advances/nmz007. Erratum in: Adv Nutr. 2020 Jul 1;11(4):1054.
  25. Manheimer EW, van Zuuren EJ, Fedorowicz Z, Pijl H. Paleolithic nutrition for metabolic syndrome: systematic review and meta-analysis. Am J Clin Nutr. 2015 Oct;102(4):922-32. doi: 10.3945/ajcn.115.113613.
  26. Genoni A, Lyons-Wall P, Lo J, Devine A. Cardiovascular, Metabolic Effects and Dietary Composition of Ad-Libitum Paleolithic vs. Australian Guide to Healthy Eating Diets: A 4-Week Randomised Trial. Nutrients. 2016 May 23;8(5):314. doi: 10.3390/nu8050314.
  27. Sohouli MH, Fatahi S, Lari A, Lotfi M, Seifishahpar M, Găman MA, Rahideh ST, AlBatati SK, AlHossan AM, Alkhalifa SA, Alomar SA, Abu-Zaid A. The effect of paleolithic diet on glucose metabolism and lipid profile among patients with metabolic disorders: a systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2022;62(17):4551-4562. doi: 10.1080/10408398.2021.1876625.
  28. Masharani U, Sherchan P, Schloetter M, Stratford S, Xiao A, Sebastian A, Nolte Kennedy M, Frassetto L. Metabolic and physiologic effects from consuming a hunter-gatherer (Paleolithic)-type diet in type 2 diabetes. Eur J Clin Nutr. 2015 Aug;69(8):944-8. doi: 10.1038/ejcn.2015.39. 
  29. Otten J, Stomby A, Waling M, Isaksson A, Söderström I, Ryberg M, Svensson M, Hauksson J, Olsson T. A heterogeneous response of liver and skeletal muscle fat to the combination of a Paleolithic diet and exercise in obese individuals with type 2 diabetes: a randomised controlled trial. Diabetologia. 2018 Jul;61(7):1548-1559. doi: 10.1007/s00125-018-4618-y.
  30. Sohouli MH, Fatahi S, Izze da Silva Magalhães E, Rodrigues de Oliveira B, Rohani P, Ezoddin N, Roshan MM, Hekmatdoost A. Adherence to a Paleolithic Diet in Combination With Lifestyle Factors Reduces the Risk for the Presence of Non-Alcoholic Fatty Liver Disease: A Case-Control Study. Front Nutr. 2022 Jul 19;9:934845. doi: 10.3389/fnut.2022.934845.
  31. Hollywood JB, Hutchinson D, Feehery-Alpuerto N, Whitfield M, Davis K, Johnson LM. The Effects of the Paleo Diet on Autoimmune Thyroid Disease: A Mixed Methods Review. J Am Nutr Assoc. 2023 Jan 4:1-10. doi: 10.1080/27697061.2022.2159570.
  32. Barone M, Turroni S, Rampelli S, Soverini M, D'Amico F, Biagi E, Brigidi P, Troiani E, Candela M. Gut microbiome response to a modern Paleolithic diet in a Western lifestyle context. PLoS One. 2019 Aug 8;14(8):e0220619. doi: 10.1371/journal.pone.0220619.
  33. Shah S, Mahamat-Saleh Y, Hajji-Louati M, Correia E, Oulhote Y, Boutron-Ruault MC, Laouali N. Palaeolithic diet score and risk of breast cancer among postmenopausal women overall and by hormone receptor and histologic subtypes. Eur J Clin Nutr. 2023 May;77(5):596-602. doi: 10.1038/s41430-023-01267-x.
  34. Sohouli MH, Baniasadi M, Hernández-Ruiz Á, Magalhães EIDS, Santos HO, Akbari A, Zarrati M. Associations of the Paleolithic Diet Pattern Scores and the Risk of Breast Cancer among Adults: A Case-Control Study. Nutr Cancer. 2023;75(1):256-264. doi: 10.1080/01635581.2022.2108466.
  35. Lavie M, Lavie I, Maslovitz S. Paleolithic diet during pregnancy-A potential beneficial effect on metabolic indices and birth weight. Eur J Obstet Gynecol Reprod Biol. 2019 Nov;242:7-11. doi: 10.1016/j.ejogrb.2019.08.013.
  36. Blomquist C, Alvehus M, Burén J, Ryberg M, Larsson C, Lindahl B, Mellberg C, Söderström I, Chorell E, Olsson T. Attenuated Low-Grade Inflammation Following Long-Term Dietary Intervention in Postmenopausal Women with Obesity. Obesity (Silver Spring). 2017 May;25(5):892-900. doi: 10.1002/oby.21815.
  37. Whalen KA, McCullough ML, Flanders WD, Hartman TJ, Judd S, Bostick RM. Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with Biomarkers of Inflammation and Oxidative Balance in Adults. J Nutr. 2016 Jun;146(6):1217-26. doi: 10.3945/jn.115.224048.
  38. Whalen KA, McCullough M, Flanders WD, Hartman TJ, Judd S, Bostick RM. Paleolithic and Mediterranean diet pattern scores and risk of incident, sporadic colorectal adenomas. Am J Epidemiol. 2014 Dec 1;180(11):1088-97. doi: 10.1093/aje/kwu235.
  39. Afifi L, Danesh MJ, Lee KM, Beroukhim K, Farahnik B, Ahn RS, Yan D, Singh RK, Nakamura M, Koo J, Liao W. Dietary Behaviors in Psoriasis: Patient-Reported Outcomes from a U.S. National Survey. Dermatol Ther (Heidelb). 2017 Jun;7(2):227-242. doi: 10.1007/s13555-017-0183-4.
  40. Lee JE, Bisht B, Hall MJ, Rubenstein LM, Louison R, Klein DT, Wahls TL. A Multimodal, Nonpharmacologic Intervention Improves Mood and Cognitive Function in People with Multiple Sclerosis. J Am Coll Nutr. 2017 Mar-Apr;36(3):150-168. doi: 10.1080/07315724.2016.1255160.
  41. Irish AK, Erickson CM, Wahls TL, Snetselaar LG, Darling WG. Randomized control trial evaluation of a modified Paleolithic dietary intervention in the treatment of relapsing-remitting multiple sclerosis: a pilot study. Degener Neurol Neuromuscul Dis. 2017 Jan 4;7:1-18. doi: 10.2147/DNND.S116949.
  42. Jönsson T, Granfeldt Y, Erlanson-Albertsson C, Ahrén B, Lindeberg S. A paleolithic diet is more satiating per calorie than a mediterranean-like diet in individuals with ischemic heart disease. Nutr Metab (Lond). 2010 Nov 30;7:85. doi: 10.1186/1743-7075-7-85.
  43. Jönsson T, Granfeldt Y, Lindeberg S, Hallberg AC. Subjective satiety and other experiences of a Paleolithic diet compared to a diabetes diet in patients with type 2 diabetes. Nutr J. 2013 Jul 29;12:105. doi: 10.1186/1475-2891-12-105.
  44. Whalen KA, Judd S, McCullough ML, Flanders WD, Hartman TJ, Bostick RM. Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with All-Cause and Cause-Specific Mortality in Adults. J Nutr. 2017 Apr;147(4):612-620. doi: 10.3945/jn.116.241919.
  45. Mårtensson A, Stomby A, Tellström A, Ryberg M, Waling M, Otten J. Using a Paleo Ratio to Assess Adherence to Paleolithic Dietary Recommendations in a Randomized Controlled Trial of Individuals with Type 2 Diabetes. Nutrients. 2021 Mar 17;13(3):969. doi: 10.3390/nu13030969.
  46. de la O V, Zazpe I, Goni L, Santiago S, Martín-Calvo N, Bes-Rastrollo M, Martínez JA, Martínez-González MÁ, Ruiz-Canela M. A score appraising Paleolithic diet and the risk of cardiovascular disease in a Mediterranean prospective cohort. Eur J Nutr. 2022 Mar;61(2):957-971. doi: 10.1007/s00394-021-02696-9.
  47. Whalen KA, Judd S, McCullough ML, Flanders WD, Hartman TJ, Bostick RM. Paleolithic and Mediterranean Diet Pattern Scores Are Inversely Associated with All-Cause and Cause-Specific Mortality in Adults. J Nutr. 2017 Apr;147(4):612-620. doi: 10.3945/jn.116.241919.
  48. Westcott WL. Resistance training is medicine: effects of strength training on health. Curr Sports Med Rep. 2012 Jul-Aug;11(4):209-16. doi: 10.1249/JSR.0b013e31825dabb8.
  49. Alfredsson L, Armstrong BK, Butterfield DA, Chowdhury R, de Gruijl FR, Feelisch M, Garland CF, Hart PH, Hoel DG, Jacobsen R, Lindqvist PG, Llewellyn DJ, Tiemeier H, Weller RB, Young AR. Insufficient Sun Exposure Has Become a Real Public Health Problem. Int J Environ Res Public Health. 2020 Jul 13;17(14):5014. doi: 10.3390/ijerph17145014.
  50. Hernández B, Scarlett S, Moriarty F, Romero-Ortuno R, Kenny RA, Reilly R. Investigation of the role of sleep and physical activity for chronic disease prevalence and incidence in older Irish adults. BMC Public Health. 2022 Sep 9;22(1):1711. doi: 10.1186/s12889-022-14108-6.
  51. Umberson D, Montez JK. Social relationships and health: a flashpoint for health policy. J Health Soc Behav. 2010;51 Suppl(Suppl):S54-66. doi: 10.1177/0022146510383501.
  52. Mariotti A. The effects of chronic stress on health: new insights into the molecular mechanisms of brain–body communication. Future Sci OA. 2015 Nov 1;1(3):FSO23. doi: 10.4155/fso.15.21.